Which medication can be used safely during lactation to treat depression?

Paroxetine is considered one of the safer options for treating depression during lactation. Studies have shown that paroxetine has a relatively low secretion into breast milk compared to other antidepressants, which means that the amount the breastfeeding infant could potentially receive is minimal. Additionally, paroxetine has been evaluated in various studies regarding its safety profile during breastfeeding, indicating that it does not typically result in significant adverse effects in breastfeeding infants.

When treating depression in breastfeeding mothers, it is crucial to select medications that balance the mental health needs of the mother with the safety of the infant. Paroxetine's established safety profile makes it a common choice, especially when compared to other antidepressants that may carry higher risks of adverse effects or greater transfer into breast milk.

While other medications may also be considered in therapy, their potential side effects or the amount that passes into breast milk can make them less desirable options during lactation.